“Informatics tools to integrate clinical trials and high throughput molecular analysis to support the transition to tailored therapy”
Progress in finding better therapies for cancer treatment is hampered by the
lack of opportunity to integrate biomedical data from disparate sources to enable
translation of therapies from bench to bedside and back. Hence, a critical factor
in the advancement of biomedical research and delivery is the ease with which data
can be integrated, redistributed and analyzed both within and across functional
domains. Novel biomedical informatics infrastructure and tools are essential for
developing individualized patient treatment regimens based on the specific genomic
signatures in each patient’s individual tumor. NCI, Center for Bioinformatics is
developing a novel translational informatics platform called caIntegrator that allows
researchers and bioinformaticians to access and analyze clinical and experimental
data across multiple clinical trials and studies. The caIntegrator framework provides
a mechanism for integrating and aggregating biomedical research data and provides access
to a variety of data types (e.g. Immunohistochemistry (IHC), microarray-based gene
expression, SNPs, clinical trials data etc.) in a cohesive fashion.
[More]
